ABSTRACT
To evaluate the demographic and clinical features of childhood pars planitis, and to determine the therapeutic and visual outcomes of the disease. Medical records of pediatric patients [less than 16 years of age at diagnosis] with pars planitis and at least 6 months of follow-up who were referred to Labbafinejad Medical Center, Tehran, Iran over a 22 year period were reviewed. Overall, 117 eyes of 61 patients including 51 [83.6%] male subjects were included. Mean age at the time of diagnosis was 7.8 +/- 3.2 [range, 3-16] years. Mean best corrected visual acuity [BCVA] was 0.88 +/- 0.76 logMAR at presentation which improved to 0.39 +/- 0.51 logMAR at final visit [P<0.001]. Endotheliitis was present in 23 [19.6%] eyes and was significantly more prevalent in subjects younger than 9 years [P=0.025]. Cataract formation [41.9%] and cystoid macular edema [19.7%] were the most prevalent complications. Univariate regression analysis showed that better baseline visual acuity [OR=0.38, 95%CI 0.21-0.70, P=0.002], age older than 5 years at disease onset [OR=0.36, 95%CI 0.14-0.9, P=0.029], absence of endotheliitis [OR=0.39, 95%CI 0.15-0.99, P-0.047] and female gender [OR=3.77, 95%CI 1.03-13.93, P=0.046] were significantly associated with final BCVA of 20/40 or better. Childhood pars planitis was much more common among male subjects. Endotheliitis may be a sign of inflammation spillover and is more prevalent in younger patients. Visual prognosis is favorable in most patients with appropriate treatment
Subject(s)
Humans , Male , Female , Pars Planitis/complications , Pars Planitis/pathology , Prognosis , Demography , Evaluation Studies as Topic , Sex Factors , Treatment Outcome , ChildABSTRACT
O edema cístico macular é uma das complicaçöes mais temíveis da pars planite, frequentemente responsável por severo e definitivo déficit visual. A importância da vitrectomia no tratamento de muitas uveítes crônicas tem sido amplamente demonstrada. Já a sua eficácia na regressäo do edema cístico macular é um assunto mais recente e polêmico. Trata-se do primeiro estudo realizado no Brasil sobre a eficácia da vitrectomia no controle do edema cístico macular associado à pars planits. Sete pacientes com edema cístico macular crônico, rebelde a todas as tentativas terapêuticas, foram submetidos à vitrectomia via pars plana e observados, sequencialmente, por no mínimo 20 e no máximo 74 meses. O edema cístico macular foi responsável pela decesäo cirúrgica. A literatura foi revisada e discutida